"When logging into and operating versaSRS "Access Denied" error prompts are being displayed."

This is caused by an ISA rule setting affecting the SOAP Requests.

The following lines of code should be included near the end of the web.config file just after the <globalisation... tag and before the end of the </system.web> tag.

<webServices>
<protocols>
<add name="HttpPost"/>
<add name="Documentation"/>
<add name="HttpSoap"/>
<add name="HttpSoap12"/>
</protocols>
</webServices>

When the above changes have been applied to the web.config file you will need to tick the "Forward the original host header instead of the actual one (specified above)" checkbox in the ISA config settings.